Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Tetrahydro-heptamethyl-naphthalenecarbaldehydes

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Photo by permission of M. Roudintska - Art & Parfum

(+)-(6R,7R)-5,6,7,8-tetrahydro-3,5,5,6,7,8,8-heptamethyl-2-naphthalenecarbaldehyde - develops a fragrance of a less earthy character, with a woody side and the strength of which is clearly inferior to the (-)-(6S,7S)-isomer

Ref: Fehr, et. al., United States Patent 5,521,151, May 28, 1996

(-)-(6S,7S)-5,6,7,8-tetrahydro-3,5,5,6,7,8,8-heptamethyl-2-naphthalenecarbaldehyde - possesses the best developed odor properties. Its musky, markedly earthy, slightly amber character is particularly powerful. It possesses a note which distinguishes itself from that of the (+)-(6R,7R) isomer

Threshold = 2.4 ppb

Ref: Fehr, et. al., United States Patent 5,521,151, May 28, 1996

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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