The BACIS Archives

[ BNB - 97021 ]


BACIS read a very interesting article called Structure-Odor Relationships by Karen J. Rossiter, an organic chemist working at Quest International (Ashford, Kent, England, TN24 0LT). This extensive review is published in Chemical Reviews (Volume 96, Number 8, pages 3201-3240, 262 references) of the American Chemical Society (Internet:
The article gives an excellent overview on the state-of-the-art developments in the field of structure-activity relationships in olfaction from around 1930 until 1996 and it is a must for every scientist who is interested in or working on structure-activity relationships in olfaction.
Reprints are available from the American Chemical Society, Washington D.C., USA ($ 25.00, ref. no. S0009-2665(95)00068-9).
Miss Rossiter can be complimented with this superb piece of work, which hopefully may introduce a new era in structure-odor relationships studies.


I. Introduction
II. The Biochemical Study of Olfaction
III. Odor Measurement
A. Physical Methods
B. Physiological Methods
C. Sensory Methods
1. Reproducibility
2. Classification of Odors
3. Gas Chromatography Olfactometry
4. Odor Intensity
IV. QSAR Studies in Specific Odor Areas
A. Ambergris
B. Bitter Almond
C. Camphoraceous
D. Floral
1. Jasmine
2. Lily of the Valley (Muguet)
3. Rose
E. Fruit
1. Esters
2. Miscellaneous
G. Musk
1. Macrocyclic Musks
2. Nitro Musk
3. Non-nitro Aromatic Benzenoids
4. SAR Studies Including Different Families of Musks
H. Wood
1. Cedarwood
2. Patchouli
3. Sandalwood
V. Concluding Remarks
VI. Acknowledgements
VII. References

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