Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 1-Methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-cyclohexanols

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Photo by permission of M. Roudintska - Art & Parfum

(-)-axial-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol - Weak, floral

= (-)-trans-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol

Ref: Christian Chapuis, In the Quest for a Virtual Pseudo Receptor for Sandalwood-Like Odorants, Part I, Chemistry & Biodiversity, Volume 1, Issue 7, Date: July 2004, Pages: 980-1021

(+)-axial-1-Methyl-4-[(1'S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol - Slightly sandalwood, weak

= (+)-trans-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol

Ref: Christian Chapuis, In the Quest for a Virtual Pseudo Receptor for Sandalwood-Like Odorants, Part I, Chemistry & Biodiversity, Volume 1, Issue 7, Date: July 2004, Pages: 980-1021

(-)-equatorial-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol - Weak

= (-)-cis-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol

Ref: Christian Chapuis, In the Quest for a Virtual Pseudo Receptor for Sandalwood-Like Odorants, Part I, Chemistry & Biodiversity, Volume 1, Issue 7, Date: July 2004, Pages: 980-1021

(+)-equatorial-1-Methyl-4-[(1'S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol - Slightly sandalwood

= (+)-cis-1-Methyl-4-[(1'S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol

Ref: Christian Chapuis, In the Quest for a Virtual Pseudo Receptor for Sandalwood-Like Odorants, Part I, Chemistry & Biodiversity, Volume 1, Issue 7, Date: July 2004, Pages: 980-1021

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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