Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 1-(2,2,6,6-Tetramethylcyclohexyloxy)-butan-2-ols

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Photo by permission of M. Roudintska - Art & Parfum

(+)-(2S)-1-[(2,2,6,6-tetramethylcyclohexyl)oxy]butan-2-ol - amber, woody, cedar, strong

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

(-)-(2R)-1-[(2,2,6,6-tetramethylcyclohexyl)oxy]buttan-2-ol - celluloid, oil cloth

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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