Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The gamma-Decalactones

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Photo by permission of M. Roudintska - Art & Parfum

(S)-(-)-4-hexylbutan-4-olide - soft sweet coconut note, fruity-fatty aspects; Bourdineaud et. al. describe this as: Fruity, banana like, lactonic and jasmonic like floral top note. Base note is closest to that of the racemate with more volume, less sweet and floral, but heavier and more lactonic.

Also known as (S)-(-)-gamma-decalactone

Ref: A. Mosandl and C. Gunther, J. Agric. Food Chem., 37, 413-416 (1989); Mans H. Boelens, Harrie Boelens & Leo J. van Gemert, Perfumer & Flavorist, Vol. 18, No. 6, 1-15, 1993; Bourdineaud, Jean-Paul; Ehret, Charles; Petrzilka, Martin; Optically active lactones, World Patent WO/94107887, April 19, 1994

(R)-(+)-4-hexylbutan-4-olide - strong, fatty-sweet fruity note, somewhat coconut, caramel; Bourdineaud et. al. describe this as: Fatty, animalic top note. Upon evaporation clearly different from the racemate with regard to the acidic and animalic base notes; In particular suitable for flavours.

Also known as (R)-(+)-gamma-decalactone

Ref: A. Mosandl and C. Gunther, J. Agric. Food Chem., 37, 413-416 (1989); Mans H. Boelens, Harrie Boelens & Leo J. van Gemert, Perfumer & Flavorist, Vol. 18, No. 6, 1-15, 1993; Bourdineaud, Jean-Paul; Ehret, Charles; Petrzilka, Martin; Optically active lactones, World Patent WO/94107887, April 19, 1994

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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