Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Jinkohol II's

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Photo by permission of M. Roudintska - Art & Parfum

(+)-(1S,2S,5R,7R,8R)-Jinkohol II - the woody note characteristic of sesquiterpenes in combination with a somewhat camphorous odor and, when heated or burnt, the characteristic odor of agarwood is strengthened

= (+)-[(1S,2S,5R,7R,8R)-2,6,6-trimethyltricyclo[6.2.1.0~1,5~]undec-7-yl]methanol

Ref: Tsukasa Nagashima & Toshio Yoshida, (+)- Or (-)-7-hydroxymethyl-2,6,6-trimethyltricyclo[6,2,1,0.sup.1,5 ]undecane, U.S. Patent No. 4,444,982 (April 24, 1984) ; J. C. Leffingwell, Chirality and odor perception - Scents of precious woods, Supplement to Chimica Oggi/CHEMISTRY TODAY Vol 24 nr 4 • Chiral technologies, pp. 36-38 (2006).

(-)-(1R,2R,5S,7S,8S)-Jinkohol II - Very similar to (+)-(1S,2S,5R,7R,8R)-Jinkohol II

= (-)-[(1R,2R,5S,7S,8S)-2,6,6-trimethyltricyclo[6.2.1.0~1,5~]undec-7-yl]methanol

Ref: Tsukasa Nagashima & Toshio Yoshida, (+)- Or (-)-7-hydroxymethyl-2,6,6-trimethyltricyclo[6,2,1,0.sup.1,5 ]undecane, U.S. Patent No. 4,444,982 (April 24, 1984) ; J. C. Leffingwell, Chirality and odor perception - Scents of precious woods, Supplement to Chimica Oggi/CHEMISTRY TODAY Vol 24 nr 4 • Chiral technologies, pp. 36-38 (2006).

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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