Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 3-mercapto-2-methyl-pentane-1-ols

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Photo by permission of M. Roudintska - Art & Parfum

(2R,3S)-3-mercapto-2-methyl-pentane-1-ol - broth-like, sweaty, leek-like;

Odor threshold = 0.04 ppb in water

The odor description appears to be for the 4 isomer mixture, but the enantiomers are differentiated by their threshold data.

Ref: Sabater-Luntzel; Christopher, et.al., J. Agric. Food Chem, 48(2), 424-427 (2000); S. Widder, et. al., U.S. Patent No. 6,231,912, May 15, 2001

(2S,3R)-3-mercapto-2-methyl-pentane-1-ol - broth-like, sweaty, leek-like;

Odor threshold = 0.03 ppb in water

The odor description appears to be for the 4 isomer mixture, but the enantiomers are differentiated by their threshold data.

Ref: Sabater-Luntzel; Christopher, et.al., J. Agric. Food Chem, 48(2), 424-427 (2000); S. Widder, et. al., U.S. Patent No. 6,231,912, May 15, 2001

(2R,3R)-3-mercapto-2-methyl-pentane-1-ol - broth-like, sweaty, leek-like;

Odor threshold = > 12 ppb in water

The odor description appears to be for the 4 isomer mixture, but the enantiomers are differentiated by their threshold data.

Ref: Sabater-Luntzel; Christopher, et.al., J. Agric. Food Chem, 48(2), 424-427 (2000); S. Widder, et. al., U.S. Patent No. 6,231,912, May 15, 2001

(2S,3S)-3-mercapto-2-methyl-pentane-1-ol - broth-like, sweaty, leek-like;

Odor threshold = >30 ppb in water

The odor description appears to be for the 4 isomer mixture, but the enantiomers are differentiated by their threshold data.

Ref: Sabater-Luntzel; Christopher, et.al., J. Agric. Food Chem, 48(2), 424-427 (2000); S. Widder, et. al., U.S. Patent No. 6,231,912, May 15, 2001

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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