Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Methyl alpha-cyclogeranates

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Photo by permission of M. Roudintska - Art & Parfum

Methyl (R)-alpha-cyclogeranate - a precious flowery, fruity, damascone-like fragrance

The racemic methyl alpha-cyclogeranate exhibits an original odour note at the same time fruity and floral and also characterized by fresh nuances of citrus type (US Patent No. 4,411,829).

Ref: Fehr, Charles; Stempf, Isabelle; Galindo, Jose, Hochenantioselektive Protonierung von Thioesterenolaten, Angew.Chem. 1993, 105: 7 1091-1093 [J. Angew. Chem., Int. Ed. Engl. 1993, 32, 1042]; Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enantioselective perception of chiral odorants, Tetrahedron: Asymmetry, 14, 1–42 (2003); Karl H. Schulte-Elte & Dietrich Kastner, Perfuming ingredient, United States Patent 4,411,829 (October 25, 1983)

Methyl (S)-alpha-cyclogeranate - characterised by a green, metallic, minty, camphoraceous note

Ref: Fehr, Charles; Stempf, Isabelle; Galindo, Jose, Hochenantioselektive Protonierung von Thioesterenolaten, Angew.Chem. 1993, 105: 7 1091-1093 [J. Angew. Chem., Int. Ed. Engl. 1993, 32, 1042]; Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enantioselective perception of chiral odorants, Tetrahedron: Asymmetry, 14, 1–42 (2003)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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