Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The methyl-Ambercore®s

1-{[2-tert-butyl-5-methylcyclohexyl]oxy}butan-2-ols

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ePhoto by permission of M. Roudintska - Art & Parfum

(+)-(1'S,2R,2'R,5'S)-5-methyl-Ambercore® - chalk, dusty, vaguely woody, weak

= (+)-(2R)-1-{[(1S,2R,5S)-2-tert-butyl-5-methylcyclohexyl]oxy}butan-2-ol

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

Ambercore® is a registered trademark of Kao Corporation

(-)-(1'R,2S,2'S,5'R)-5-methyl-Ambercore® - amber, woody, not very powerful

= (-)-(2S)-1-{[(1R,2S,5R)-2-tert-butyl-5-methylcyclohexyl]oxy}butan-2-ol

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

Ambercore® is a registered trademark of Kao Corporation

(-)-(1'R,2R,2'S,5'R)-5-methyl-Ambercore® - floral, vague

= (-)-(2R)-1-{[(1R,2S,5R)-2-tert-butyl-5-methylcyclohexyl]oxy}butan-2-ol

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

Ambercore® is a registered trademark of Kao Corporation

(+)-(1'S,2S,2'R,5'S)-5-methyl-Ambercore® - floral, vague

= (+)-(2S)-1-{[(1S,2R,5S)-2-tert-butyl-5-methylcyclohexyl]oxy}butan-2-ol

Ref: Christian Margot, Dana P. Simmonsb, Daniel Reichlinc and David Skuya, Amber-Woody Scent: Alcohols with Divergent Structure Present Common Olfactory Characteristics and Sharp Enantiomer Differentiation, Helvetica Chimica Acta, Vol. 87, 2662-2684 (2004)

Ambercore® is a registered trademark of Kao Corporation

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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