(-)-(4S,4aR,6S)-nootkatone - weak woody (vetiver note); no grapefruit character; virtually no taste; On an odor rating scale: Dusty-woody, spicy, slightly fresh, green, sour, herbal = (-)-(4S,4aR,6S)-6-Isopropenyl-4,4a-dimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one Odor Threshold = 600000 ppb (Average of values) Ref: H.G. Haring, F. Rijkens & H. Boelens, Olfactory Studies on Enantiomeric Eremophilane Sesquiterpenoids, J. Agric. Food Chem., 20, 1018 (1972); Mans H. Boelens, Harrie Boelens & Leo J. van Gemert, Perfumer & Flavorist, Vol. 18, No. 6, 1-15, 1993

(+)-(4R,4aS,6R)-nootkatone - strong grapefruit odor, bitter in taste On an odor rating scale: Strongly fresh, green, sour; dusty-woody; animal-erogenic, slightly herbal, fruity = (+)- (4R,4aS,6R)-6-Isopropenyl-4,4a-dimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one Odor Threshold = 800 ppb (Average of values) (+)- and (-)-nootkatone have been tasted in a soft drink base by several experienced flavor chemists. (+)-Nootkatone was perceptible at a concentration of approximately 0.3 ppm and still had the flavor character of grapefruit. (-)-Nootkatone was perceptible at 40 ppm (much lower than the odor threshold value for aqueous solutions) and at that concentration tasted bitter and sour without any flavor impression. Ref: H.G. Haring, F. Rijkens & H. Boelens, Olfactory Studies on Enantiomeric Eremophilane Sesquiterpenoids, J. Agric. Food Chem., 20, 1018 (1972); Mans H. Boelens, Harrie Boelens & Leo J. van Gemert, Perfumer & Flavorist, Vol. 18, No. 6, 1-15, 1993

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants