Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 3-((Dimethyl(2,3-dimethylbutan-2-yl)silyl)methyl)butan-2-ols

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Photo by permission of M. Roudintska - Art & Parfum

(2R,3R)-3-((dimethyl(2,3-dimethylbutan-2-yl)silyl)methyl)butan-2-ol - camphoraceous-earthy and green odor, slightly sweaty and somewhat floral

Ref: Leszek Doszczak, Tecla Gasperi, Alexandre Saint-Dizier, M. Antonietta Loreto, Dieter Enders, Silylating Reagents: A Powerful Tool for the Construction of Isosteric Analogs of Highly Branched Odorants, in Perspectives in flavor and fragrance research, Philip Kraft, Karl A. D. Swift, Eds., Wiley-VCH, 2005, p. 98; Leszek Doszczak, Tecla Gasperi, Alexandre Saint-Dizier, M. Antonietta Loreto, Dieter Enders, Silylating Reagents: A Powerful Tool for the Construction of Isosteric Analogs of Highly Branched Odorants, Chemistry & Biodiversity, Volume 1, Issue 12, Date: December 2004, Pages: 1921-1935

 

(2S,3S)-3-((dimethyl(2,3-dimethylbutan-2-yl)silyl)methyl)butan-2-ol - more earthy-mouldy than camphoraceous, with fruity green-metallic nuances

Ref: Leszek Doszczak, Tecla Gasperi, Alexandre Saint-Dizier, M. Antonietta Loreto, Dieter Enders, Silylating Reagents: A Powerful Tool for the Construction of Isosteric Analogs of Highly Branched Odorants, in Perspectives in flavor and fragrance research, Philip Kraft, Karl A. D. Swift, Eds., Wiley-VCH, 2005, p. 98; Leszek Doszczak, Tecla Gasperi, Alexandre Saint-Dizier, M. Antonietta Loreto, Dieter Enders, Silylating Reagents: A Powerful Tool for the Construction of Isosteric Analogs of Highly Branched Odorants, Chemistry & Biodiversity, Volume 1, Issue 12, Date: December 2004, Pages: 1921-1935

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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