Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 1,2',7,7-tetramethyl- spirobicyclo[2.2.1]heptane-2,4'-[1,3]dioxanes

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Photo by permission of M. Roudintska - Art & Parfum

(-)-(1R,2S,2'S,4R)-1,2',7,7-tetramethyl-spiro[bicyclo[2.2.1]heptane-2,4'-[1,3]dioxane] - Woody, ambery, camphor, animal, earthy/mossy, musky

 98% of 1R,2S,2'S,4R isomer + 2% 1R,2S,2'R,4R isomer

 Ref: Bajgrowicz; Jerzy A., Odorants, United States Patent 5,703,250 (December 30, 1997 )

 

(+)-(1S,2R,2'R,4S)-1,2',7,7-tetramethyl-spiro[bicyclo[2.2.1]heptane-2,4'-[1,3]dioxane] - Woody, animal, camphor, ambery, earthy/mossy, fruity

>92% of 1S,2R,2'R,4S isomer + <8% 1S,2R,2'S,4S isomer

 Ref: Bajgrowicz; Jerzy A., Odorants, United States Patent 5,703,250 (December 30, 1997 )

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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