Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Tetrahydronootkatones

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Photo by permission of M. Roudintska - Art & Parfum

((+)-(4R,4aS,6R,8aS)-Tetrahydronootkatone - dusty-woody, fresh, green, sour, spicy, herbal, slightly fruity, animal, erogenic

Threshold (in water) = 5000-20000 ppb

= (+)-(4R,4aS,6R,8aS)-6-isopropyl-4,4a-dimethyloctahydronaphthalen-2(1H)-one

Ref: H.G. Haring, F. Rijkens & H. Boelens, J. Agric. Food Chem., 20, 1018-1021 (1972)

(-)-Tetrahydronootkatone - dusty-woody, spicy, fresh, green, sour, slightly herbal, fruity, animal, erogenic

Threshold (in water) = 30000-70000 ppb

= (-)-(4S,4aR,6S,8aR)-6-isopropyl-4,4a-dimethyloctahydronaphthalen-2(1H)-one

Ref: H.G. Haring, F. Rijkens & H. Boelens, J. Agric. Food Chem., 20, 1018 (1972)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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