Chirality & Odour Perception
John C. Leffingwell, Ph.D.

Trimethylcyclohexyl-pentan-3-ols

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Photo by permission of M. Roudintska - Art & Parfum

(1'R,6'S)-(+)-1-(2',2',6'-Trimethyl-cyclohexyl)-pentan-3-ol - very diffusive sharp amber odor with slight orrisy camphoraceous side note

Odor Threshold = 56 ppb

 

Note that the C-3 position is epimeric, so this actually is a mixture of (1'R,3S,6'S) & (1'R,3R,6'S) isomers

Ref: T. Yamamoto, H. Matsuda, T. Ohmoto, A. Shimada & T. Sato, Proc. 12th Int. Congress of Flavours, Fragrances & Essential oils, Vienna, Austria, Oct. 4-8, 1992, pp.442-455

(1'S,6'R)-(-)-1-(2',2',6'-Trimethyl-cyclohexyl)-pentan-3-ol - faint vetiver-like woody odor with slight amber and moldy note

 Odor Threshold = 890 ppb

Note that the C-3 position is epimeric, so this actually is a mixture of (1'S,3R,6'R) & (1'S,3S,6'R) isomers

Ref: T. Yamamoto, H. Matsuda, T. Ohmoto, A. Shimada & T. Sato, Proc. 12th Int. Congress of Flavours, Fragrances & Essential oils, Vienna, Austria, Oct. 4-8, 1992, pp.442-455

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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